Spyre Therapeutics, Inc. (SYRE)
Listed in the US · Manufacturing · Pharmaceutical preparations
$98.96
As of 29 Oct 2026 close.
Facts from reported results and exchange filings. Not investment advice.
Share price
Prices load here as you scroll to them.
Last close $98.96 on 29 Oct 2026. The share price traded between $21.15 and $110.18 (intraday) over the last 12 months.
The closes as a table
| Date | Close |
|---|
Key figures
1-year range (intraday)
Low $21.15High $110.18
Revenue is very small next to this company's costs or profit, so its margins here are extreme figures (beyond ±100%). They are what the reported numbers give, but they say little about how the business earns.
Price trend
- Stage 2 (advancing): the price is above a rising 150-day average, for 9 trading days.
- Supertrend (10, 3): the price has closed above the line for 3 trading days.
Revenue and profit
| Year | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|
| Revenue | 19 | 2 | 1 | 0 | 0 |
| Net profit | -66 | -84 | -339 | -208 | -155 |
| EBITDA margin | -341.9% | n/m | n/m | – | – |
| Borrowings | – | – | 0 | 0 | 0 |
$ million.
Recent filings
- 4 Aug 2026
Earnings release (8-K) - 4 Aug 2026
Quarterly report (10-Q) - 5 May 2026
Earnings release (8-K) - 5 May 2026
Quarterly report (10-Q) - 13 Apr 2026
Earnings release (8-K) - 19 Feb 2026
Earnings release (8-K)
Questions about Spyre Therapeutics, Inc.
What is Spyre Therapeutics, Inc.'s market value?
Spyre Therapeutics, Inc.'s market value is $8.7B as of 29 Oct 2026 close: the last close times the shares in issue.
When are Spyre Therapeutics, Inc.'s next results?
Spyre Therapeutics, Inc.'s next results are listed for 3 Nov 2026 (the exchange's notice: Quarterly results (quarter ended Sep 2026)). Dates are as the company announced them, on the list of 30 Oct 2026.
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Same industry
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How these figures are worked out
- Last close: the closing price on the date shown. The page follows the market's close; it doesn't show prices during the session. A price older than the market's latest close, or a last trade that isn't a close, is labelled as the last price, with the session it is from.
- 1-year range: the lowest and highest prices traded during the sessions of the last year (intraday), so they can lie outside the closing prices.
- Market cap: the last close times the shares in issue. It is n/a when it doesn't agree with the company's own reported figures (for example a depositary share counted as an ordinary share).
- P/E: the last close divided by earnings per share over the last four reported quarters, the profit that belongs to the company's shareholders per share, as the company reports it. So P/E can differ from market cap divided by the net profit shown (a different share count, or the profit before minority interests; where they differ by more than 10%, a note under the figures gives both). A company that reports only once a year has its latest year's earnings, and the P/E names that year; when that year ended more than about 15 months before the close, P/E is n/a. A loss has no P/E. Above 1,000 it is n/a.
- EBITDA margin: operating profit before depreciation, interest and tax (and before other income), as a share of revenue in the latest reported year, the table's last column.
- Net margin: net profit as a share of revenue in the latest reported period. Return on equity, the margins and debt to equity each use inputs from that one year; if one input is missing for it, the figure is n/a. When that year ended more than about 15 months before the close, they are n/a too.
- Dividend yield: every dividend per share with an ex-date in the 12 months to the last close, special dividends included, as a share of that close. n/a when the company's dividends couldn't be read.
- n/m: not meaningful. A margin or return beyond ±1,000% comes from revenue or equity near zero, so it is not shown as a number.